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Cat. No.: HY-170868

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CL2A-FL118

CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118.

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CAS No.: 3025194-00-4
화학식: C₇₂H₉₃N₁₁O₂₃
분자량:1480.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CL2A-FL118 Chemical Structure

CAS No.: 3025194-00-4

사이즈

가격

재고

수량

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Use of MCE Products

One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

제품 설명

CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 3025194-00-4
분자량 1480.57
화학식 C₇₂H₉₃N₁₁O₂₃
SMILES

O=C(OCC1=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O)=O)C=C1)O[C@](C5=C(CO6)C(N7CC8=CC9=CC%10=C(OCO%10)C=C9N=C8C7=C5)=O)(CC)C6=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mathi GR, et al. Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy. Bioorg Med Chem Lett. 2025 Apr 1;118:130085. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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CL2A-FL118

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CL2A-FL118 Related Classifications

HY-170868 Related Classifications