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Cat. No.: HY-P992530

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CM355

Name: CM355
Brand: MedChemExpress
SKU: HY-P992530
Availability: PreOrder

(Synonyms: ICP-B02)

CM355 (ICP-B02) is a CD20/CD3 bispecific IgG4 antibody. CM355 exhibits asymmetric affinity binding to CD20 and CD3. CM355 does not bind to Fcγ receptors (FcγR), which is designed to reduce the risk of cytokine release. CM355 can be used for research on B-cell non-Hodgkin lymphoma.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CM355 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- 제품 설명
- Species Reactivity
- In Vitro
- Target
- Conjugated
- 신청
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Species Reactivity

Human

In Vitro

Adaptive Immunity

CM355 eliminates malignant B cells by inducing T cell-dependent cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Inflammation-related Diseases

Target

CD3 & CD20

Conjugated

Unconjugated

신청

ELISA, FACS, Functional assay

Chemical Information

SMILES

[CM355]
Synonyms

ICP-B02
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Inhibitory Antibodies User Guide (603 KB)

References

[1]. SUBCUTANEOUS CM355, A NOVEL BISPECIFIC CD20/CD3 ANTIBODY
SHOWED PROMISING EFFICACY AND FAVORABLE SAFETY PROFILE IN
RELAPSED/REFRACTORY B-CELL NON-HODGKIN LYMPHOMA. EHA Library.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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