Collinin
Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains.
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- CAS No.: 34465-83-3
- 화학식: C20H24O4
- 분자량:328.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
5.9 μM
Compound: collinin
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Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production
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[PMID: 28844340] |
Collinin significantly inhibits the growth of MDR and XDR M. tuberculosis in the culture broth with 50% minimum inhibitory concentrations (MIC50s) of 3.13-6.25 µg/mL[1].
Collinin inhibits the growth of intracellular drug-susceptible and drug-resistant tuberculosis in Raw264.7 and A549 cells with MIC50s of 6.25-12.50 µg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 34465-83-3
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분자량 328.40
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화학식 C20H24O4
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SMILES
O=C1C=CC2=CC=C(OC/C=C(C)/CC/C=C(C)/C)C(OC)=C2O1
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Collinin Related Classifications
HY-N8388 Related Classifications
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