DAT-003
DAT-003 is a MRGPRX2 antagonist that selectively blocks MRGPRX2-mediated, IgE-independent mast cell degranulation without affecting IgE-dependent activation. DAT-003 can be used in studies of mast cell-related diseases, such as chronic spontaneous urticaria.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C27H30F2N6O3
- 분자량:524.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
In Vitro
DAT-003 potently inhibits MRGPRX2 activation in a concentration-dependent manner across multiple cell lines, including HEK293 cells overexpressing MRGPRX2 and primary human mast cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 524.56
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화학식 C27H30F2N6O3
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SMILES
FC1=CC(F)=CC([C@@H]2N3C(CC2)=NC(NC([C@H](C)N4CCN(C(C5=CC=[N+]([O-])C=C5)=O)C(C)(C)C4)=O)=C3)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DAT-003 Related Classifications
HY-189392 Related Classifications
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