EF1500
EF1500 is a potent human GABA transporter 1 (hGAT1) inhibitor and a lipophilic THPO analog. EF1500 occupies the binding site by forming a hydrogen bond with active residues of hGAT1 (such as Tyr139) through its exocyclic amino group, thereby blocking GABA reuptake. EF1500 can be used for research on central nervous system diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 738562-57-7
- 화학식: C21H24N2O2S2
- 분자량:400.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
EF1500 binds effectively to hGAT1, with a binding energy of -9.19 kcal/mol for R-EF1500 to hGAT1 and -8.34 kcal/mol for S-EF1500 to hGAT1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 738562-57-7
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분자량 400.56
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화학식 C21H24N2O2S2
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SMILES
O=C1NOC2=C1C(NCCC=C(C=3SC=CC3C)C=4SC=CC4C)CCC2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EF1500 Related Classifications
HY-189042 Related Classifications
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