FR 76830
FR 76830 is a bradycardic agent with cardiomyocyte protective effects. FR 76830 attenuates the decrease in myocardial pH during the early stage of ischemia. FR 76830 improves ATP levels during the late stage of ischemia. FR 76830 reduces heart rate in a dose-dependent manner without decreasing the rate-pressure product of the myocardium. FR 76830 exerts cardioprotective effects during ischemia and reperfusion. FR 76830 can be used for the research of myocardial ischemia-reperfusion injury.
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- CAS No.: 113243-75-7
- 화학식: C25H26N4O4
- 분자량:446.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
FR 76830 (22.4-67.2 μM) exerts independent myocardial protective effects by simply slowing heart rate without reducing myocardial oxygen consumption (unchanged DP), alleviating early ischemic acidosis, delaying late ATP depletion, and promoting ATP recovery during reperfusion[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 113243-75-7
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분자량 446.50
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화학식 C25H26N4O4
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SMILES
O=C(NCCN1CCOCC1)C2=C(C)N=C(C3=CC=CC=C3)C=C2C4=CC=CC([N+]([O-])=O)=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FR 76830 Related Classifications
HY-116960 Related Classifications
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