ANKRD44 - ankyrin repeat domain 44 Gene

Also Known as PP6-ARS-B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 91526

About ANKRD44

This gene has 13 transcripts (splice variants), 206 orthologues and 3 paralogues. Broad expression in lymph node (RPKM 12.0), appendix (RPKM 9.6) and 23 other tissues.

ANKRD44 Products (5)

mRNA Protein Name
NM_001195144.2 NP_001182073.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform A
NM_001367495.1 NP_001354424.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform C
NM_001367496.1 NP_001354425.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform D
NM_001367497.1 NP_001354426.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform E
NM_153697.3 NP_710181.2 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform B

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16555005 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANKRD44 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (4 - 96)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (100 - 162)

Ank

Ank: Ankyrin repeat (168 - 196)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (206 - 293)

Ank

Ank: Ankyrin repeat (330 - 357)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (367 - 427)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (428 - 473)

Ank_4

Ank_4: Ankyrin repeats (many copies) (506 - 544)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (560 - 622)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (630 - 722)

Ank

Ank: Ankyrin repeat (728 - 749)

Ank

Ank: Ankyrin repeat (764 - 787)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (800 - 895)

Ank

Ank: Ankyrin repeat (898 - 919)

Ank

Ank: Ankyrin repeat (935 - 964)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 985 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

  • ankyrin repeat domain-containing protein 44

ANKRD44 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ANKRD44 Q8N8A2 PPP6R1 Homo sapiens Q9UPN7
Anti Tag CoIP
33961781
Intra
ANKRD44 Q8N8A2 WWP2 Homo sapiens O00308
Y2H Array
31515488
Intra
ANKRD44 Q8N8A2 WWP2 Homo sapiens O00308
Y2H Array
25416956
Intra
ANKRD44 Q8N8A2 WWP2 Homo sapiens O00308
Y2H Prey Pooling
25416956
Intra
ANKRD44 Q8N8A2 USP6 Homo sapiens P35125-3
Pull Down
16555005
Intra
ANKRD44 Q8N8A2 USP6 Homo sapiens P35125-3
Anti Tag CoIP
16555005
Intra
ANKRD44 Q8N8A2 USP6 Homo sapiens P35125-3
Confocal
16555005
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 4

  • ETL4

  • Epilepsy, Occipitotemporal Lobe, And Migraine With Aura

  • Epolm

  • Familial Temporal Lobe Epilepsy 4

  • Occipitotemporal Lobe Epilepsy And Migraine With Aura
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS00729 ANKRD44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ANKRD44 RGD RGD:1561893
Canis familiaris ANKRD44 VGNC VGNC:57373
Felis catus ANKRD44 VGNC VGNC:80135
Mus musculus ANKRD44 MGD MGI:3045243
Macaca mulatta ANKRD44 VGNC VGNC:84209
Bos taurus ANKRD44 VGNC VGNC:55324
Others ANKRD44 NCBI