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Cat. No.: HY-155825

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LPE-1

LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC₅₀ of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1637373-70-6
화학식: C₁₃H₁₀N₆S₃
분자량:346.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

LPE-1 Chemical Structure

CAS No.: 1637373-70-6

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

LPE-1 (Compound Ⅰ-12) (72 h) inhibits the proliferation of MGC-803 (IC₅₀ = 7.85 μM), HGC-27 (IC₅₀ = 5.16 μM), HepG2 (IC₅₀ = 5.71 μM) and PC-3 (IC₅₀ = 7.21 μM) cells, but shows no detectable activity against SGC-7901 cells (IC₅₀ >128 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1637373-70-6
분자량 346.45
화학식 C₁₃H₁₀N₆S₃
SMILES

N#CC=1C(=NC(=NC1C=2SC=CC2)SCC#C)NNC(=S)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Liu, et al. Pyrimidine derivatives containing semicarbazide and terminal alkyne structural units, and preparation methods and applications of pyrimidine derivatives. CN104119280 A.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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