ZD-2767P
Based on 1 Customer Validation
ZD-2767P (Compound 1) is a reversible and competitive inhibitor of IDH1, with its IC50 value being 410 nM.
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- CAS No.: 156079-88-8
- 화학식: C16H20I2N2O6
- 분자량:590.15
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보관:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LoVo | IC50 |
47.2 μM
Compound: 1b
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Cytotoxicity against colorectal tumor cell line LoVo 1 hour after incubation.
Cytotoxicity against colorectal tumor cell line LoVo 1 hour after incubation.
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[PMID: 8544182] |
Chemical Information
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CAS No. 156079-88-8
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Appearance Solid
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분자량 590.15
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화학식 C16H20I2N2O6
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Color Light yellow to yellow
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SMILES
O=C(O)CC[C@@H](C(O)=O)NC(OC1=CC=C(N(CCI)CCI)C=C1)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
용액&용해도
DMSO : 25 mg/mL (42.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6945 mL | 8.4724 mL | 16.9448 mL | 42.3621 mL |
| 5 mM | 0.3389 mL | 1.6945 mL | 3.3890 mL | 8.4724 mL | |
| 10 mM | 0.1694 mL | 0.8472 mL | 1.6945 mL | 4.2362 mL | |
| 15 mM | 0.1130 mL | 0.5648 mL | 1.1297 mL | 2.8241 mL | |
| 20 mM | 0.0847 mL | 0.4236 mL | 0.8472 mL | 2.1181 mL | |
| 25 mM | 0.0678 mL | 0.3389 mL | 0.6778 mL | 1.6945 mL | |
| 30 mM | 0.0565 mL | 0.2824 mL | 0.5648 mL | 1.4121 mL | |
| 40 mM | 0.0424 mL | 0.2118 mL | 0.4236 mL | 1.0591 mL |
ZD-2767P Related Classifications
HY-19208 Related Classifications
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