L-Lysine-¹⁵N-1 dihydrochloride

Name: L-Lysine- 15 N-1 dihydrochloride
Brand: MedChemExpress
SKU: HY-N0469S2
Rating: 4.5 (0 reviews)

Cat. No.: HY-N0469S2 Purity: 98.0%: Data Sheet
COA

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Handling Instructions
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L-Lysine-¹⁵N-1 (dihydrochloride) is the ¹⁵N-labeled L-Lysine. L-lysine is an essential amino acid with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions.

For research use only. We do not sell to patients.

L-Lysine-<sup>15</sup>N-1 dihydrochloride

L-Lysine-¹⁵N-1 dihydrochloride Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Other Forms of L-Lysine-¹⁵N-1 dihydrochloride:

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Purity & Documentation
References
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Description

L-Lysine-¹⁵N-1 (dihydrochloride) is the ¹⁵N-labeled L-Lysine. L-lysine is an essential amino acid^[1]^[2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions^[2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

220.10

Formula

C₆H₁₆Cl₂N¹⁵NO₂

Unlabeled CAS

56-87-1

Appearance

Solid

SMILES

[15NH2]CCCC[C@H](N)C(O)=O.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 125 mg/mL (567.92 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5434 mL	22.7169 mL	45.4339 mL
5 mM	0.9087 mL	4.5434 mL	9.0868 mL
10 mM	0.4543 mL	2.2717 mL	4.5434 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.0%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (241 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.5434 mL	22.7169 mL	45.4339 mL	113.5847 mL
	5 mM	0.9087 mL	4.5434 mL	9.0868 mL	22.7169 mL
	10 mM	0.4543 mL	2.2717 mL	4.5434 mL	11.3585 mL
	15 mM	0.3029 mL	1.5145 mL	3.0289 mL	7.5723 mL
	20 mM	0.2272 mL	1.1358 mL	2.2717 mL	5.6792 mL
	25 mM	0.1817 mL	0.9087 mL	1.8174 mL	4.5434 mL
	30 mM	0.1514 mL	0.7572 mL	1.5145 mL	3.7862 mL
	40 mM	0.1136 mL	0.5679 mL	1.1358 mL	2.8396 mL
	50 mM	0.0909 mL	0.4543 mL	0.9087 mL	2.2717 mL
	60 mM	0.0757 mL	0.3786 mL	0.7572 mL	1.8931 mL
	80 mM	0.0568 mL	0.2840 mL	0.5679 mL	1.4198 mL
	100 mM	0.0454 mL	0.2272 mL	0.4543 mL	1.1358 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.