L-Lysine sulfite
Based on 7 publication(s) in Google Scholar
L-lysine sulfite is an essential amino acid for humans, offers numerous benefits and can be used in herpes research. Additionally, L-lysine sulfite enhances calcium absorption, reduces diabetes-related complications, improves gut health, and alleviates pancreatitis inflammation.
For research use only. We do not sell to patients.
- CAS No.: 53411-64-6
- Formula: C6H14N2O2S.1/2H2O3S
- Molecular Weight:228.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Lysine sulfite
More- Nature. 2025 Jul;643(8070):192-200. [Abstract]
- Vet Microbiol. 2026 May:316:110992. [Abstract]
- Cell Biochem Biophys. 2025 May 30. [Abstract]
- Amino Acids. 2024 Sep 18;56(1):56. [Abstract]
- iMetaOmics. 2025 Aug 06.
- Patent. US20240216332A1.
- Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.
Customer Validation & Images
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In Vivo Efficacy Study
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IF
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Cell Migration/Invasion Assay
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WB
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Microbiological Assay
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Acute pancreatitis mice model[3]
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Dosage:10 mg/kg
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Administration:Oral gavage (p.o.), pre-treated or post-treated
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Result:Led to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement was observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione (p < 0.001).
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Animal Model:a Lipopolysaccharide (HY-D1056) -induced mouse model[4]
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Dosage:5 mg/kg, 10 mg/kg
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Administration:Oral gavage (p.o.), 45 days
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Result:Significantly reduced lipid peroxidation, total protein content, lung tissue wet/dry ratio, tumor necrosis factor-alpha, interleukin-8, and macrophage inhibitory factor levels, myeloperoxidase activity, as well as total cell, neutrophil, and lymphocyte counts. Additionally, L-lysine increased the levels of reduced glutathione and the activities of glutathione peroxidase, superoxide dismutase, and catalase.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 53411-64-6
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Molecular Weight 228.27
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Formula C6H14N2O2S.1/2H2O3S
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SMILES
N[C@@H](CCCCN)C(O)=O.O=S(O)O.[0.5]
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (7)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Vet Microbiol
The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]2026 May:316:110992. PMID: 41865607 -
Cell Biochem Biophys
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression. [Abstract]2025 May 30. PMID: 40445264 -
Amino Acids
Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus. [Abstract]2024 Sep 18;56(1):56. PMID: 39292313 -
L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Serum FITC-dextran levels were reduced upon L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation, indicating improved barrier function. L-Lysine also partially reversed the weight loss.
L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Representative immunofluorescence images of ZO-1 and red mean density analysis of ZO-1 in the ileum and colon. L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation significantly restored ZO-1 density.
L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Effect of L-Lysine (1.4 mM; 12 h) intervention on the scratch injury healing rate of IFN-γ pre-processed and NCM-460 cells. IFN‐γ significantly impaired healing in NCM-460 cells, and this effect was significantly alleviated by L‐Lysine.
L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Effects of L-Lysine (1.4 mM; 24 h) intervention on the ZO-1 and Occludin expression of IFN-γ pre-processed HIEC-6 cells by western blot.
L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
L-Lysine (0.7-2.8 mM) dose-dependently inhibits H.biformis growth in vitro.
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Purity & Documentation
References
[1]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [Content Brief]
[3]. https://www.ncbi.nlm.nih.gov/pubmed/28538804 [Content Brief]
[4]. Zhang Y, et al. L-lysine ameliorates sepsis-induced acute lung injury in a lipopolysaccharide-induced mouse model. Biomed Pharmacother. 2019 Oct;118:109307. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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