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  3. L-Lysine sulfite

L-lysine sulfite is an essential amino acid for humans, offers numerous benefits and can be used in herpes research. Additionally, L-lysine sulfite enhances calcium absorption, reduces diabetes-related complications, improves gut health, and alleviates pancreatitis inflammation.

For research use only. We do not sell to patients.

CAS No. : 53411-64-6

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Top Publications Citing Use of Products

    L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Serum FITC-dextran levels were reduced upon L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation, indicating improved barrier function. L-Lysine also partially reversed the weight loss.

    L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Representative immunofluorescence images of ZO-1 and red mean density analysis of ZO-1 in the ileum and colon. L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation significantly restored ZO-1 density.

    L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Effect of L-Lysine (1.4 mM; 12 h) intervention on the scratch injury healing rate of IFN-γ pre-processed and NCM-460 cells. IFN‐γ significantly impaired healing in NCM-460 cells, and this effect was significantly alleviated by L‐Lysine.

    L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Effects of L-Lysine (1.4 mM; 24 h) intervention on the ZO-1 and Occludin expression of IFN-γ pre-processed HIEC-6 cells by western blot.

    L-Lysine sulfite purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    L-Lysine (0.7-2.8 mM) dose-dependently inhibits H.biformis growth in vitro.

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    Description

    L-lysine sulfite is an essential amino acid for humans[1][2], offers numerous benefits and can be used in herpes research. Additionally, L-lysine sulfite enhances calcium absorption, reduces diabetes-related complications, improves gut health, and alleviates pancreatitis inflammation[2][3].

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vivo

    L-lysine (10 mg/kg, p.o., pre-treated or post-treated) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity in acute pancreatitis mice model[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Acute pancreatitis mice model[3]
    Dosage: 10 mg/kg
    Administration: Oral gavage (p.o.), pre-treated or post-treated
    Result: Led to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement was observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione (p < 0.001).
    Animal Model: a Lipopolysaccharide (HY-D1056) -induced mouse model[4]
    Dosage: 5 mg/kg, 10 mg/kg
    Administration: Oral gavage (p.o.), 45 days
    Result: Significantly reduced lipid peroxidation, total protein content, lung tissue wet/dry ratio, tumor necrosis factor-alpha, interleukin-8, and macrophage inhibitory factor levels, myeloperoxidase activity, as well as total cell, neutrophil, and lymphocyte counts. Additionally, L-lysine increased the levels of reduced glutathione and the activities of glutathione peroxidase, superoxide dismutase, and catalase.
    Clinical Trial
    Molecular Weight

    228.27

    Formula

    C6H14N2O2S.1/2H2O3S

    CAS No.
    SMILES

    N[C@@H](CCCCN)C(O)=O.O=S(O)O.[0.5]

    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
    References
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    L-Lysine sulfite
    Cat. No.:
    HY-N0469A
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