LNK4-S
Based on 1 Customer Validation
LNK4-S is a drug-linker conjugate, that can be used for synthesis of ADC molecule M-VA-EXA and F-VA-EXA.
For research use only. We do not sell to patients.
- Purity: 96.41%
- CAS No.: 2845165-06-0
- Formula: C91H121FN20O28
- Molecular Weight:1962.05
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADC (antibody-drug conjugate) combines monoclonal antibodies, potent cytotoxic drugs and linkers to achieve precise targeting of tumor cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2845165-06-0
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Appearance Solid
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Molecular Weight 1962.05
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Formula C91H121FN20O28
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Color White to off-white
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SMILES
OC(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C([C@@H](NC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)CCC(NC[C@H](C2=CC=C(C=C2)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)OC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (50.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5097 mL | 2.5484 mL | 5.0967 mL | 12.7418 mL |
| 5 mM | 0.1019 mL | 0.5097 mL | 1.0193 mL | 2.5484 mL | |
| 10 mM | 0.0510 mL | 0.2548 mL | 0.5097 mL | 1.2742 mL | |
| 15 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8495 mL | |
| 20 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.6371 mL | |
| 25 mM | 0.0204 mL | 0.1019 mL | 0.2039 mL | 0.5097 mL | |
| 30 mM | 0.0170 mL | 0.0849 mL | 0.1699 mL | 0.4247 mL | |
| 40 mM | 0.0127 mL | 0.0637 mL | 0.1274 mL | 0.3185 mL | |
| 50 mM | 0.0102 mL | 0.0510 mL | 0.1019 mL | 0.2548 mL |
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