LNK4-S
Based on 1 Customer Validation
LNK4-S is a drug-linker conjugate, that can be used for synthesis of ADC molecule M-VA-EXA and F-VA-EXA.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.78%
- CAS 番号: 2845165-06-0
- 分子式: C91H121FN20O28
- 分子量:1962.05
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
ADC (antibody-drug conjugate) combines monoclonal antibodies, potent cytotoxic drugs and linkers to achieve precise targeting of tumor cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2845165-06-0
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性状 Solid
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分子量 1962.05
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分子式 C91H121FN20O28
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Color White to off-white
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SMILES
OC(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C([C@@H](NC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)CCC(NC[C@H](C2=CC=C(C=C2)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)OC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (50.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5097 mL | 2.5484 mL | 5.0967 mL | 12.7418 mL |
| 5 mM | 0.1019 mL | 0.5097 mL | 1.0193 mL | 2.5484 mL | |
| 10 mM | 0.0510 mL | 0.2548 mL | 0.5097 mL | 1.2742 mL | |
| 15 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8495 mL | |
| 20 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.6371 mL | |
| 25 mM | 0.0204 mL | 0.1019 mL | 0.2039 mL | 0.5097 mL | |
| 30 mM | 0.0170 mL | 0.0849 mL | 0.1699 mL | 0.4247 mL | |
| 40 mM | 0.0127 mL | 0.0637 mL | 0.1274 mL | 0.3185 mL | |
| 50 mM | 0.0102 mL | 0.0510 mL | 0.1019 mL | 0.2548 mL |