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  5. LPE-1

LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer.

For research use only. We do not sell to patients.

LPE-1

LPE-1 Chemical Structure

CAS No. : 1637373-70-6

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LPE-1 Related Antibodies

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Description

LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer[1].

In Vitro

LPE-1 (Compound Ⅰ-12) (72 h) inhibits the proliferation of MGC-803 (IC50 = 7.85 μM), HGC-27 (IC50 = 5.16 μM), HepG2 (IC50 = 5.71 μM) and PC-3 (IC50 = 7.21 μM) cells, but shows no detectable activity against SGC-7901 cells (IC50 >128 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LPE-1 Related Antibodies
Molecular Weight

346.45

Formula

C13H10N6S3
CAS No.
SMILES

N#CC=1C(=NC(=NC1C=2SC=CC2)SCC#C)NNC(=S)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LPE-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LPE-11637373-70-6LPE1LPE 1HepG2liver cancergastric cancerHGC-27prostate cancer cellsprostate cancerMGC-803gastric cancer cellsliver cancer cellslysine-specific demethylase 1Inhibitorinhibitorinhibit

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LPE-1
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HY-155825
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