Mal-βAla-β-glucuronide-MMAE
Based on 1 Customer Validation
Mal-βAla-β-glucuronide-MMAE is a drug-linker conjugate. Mal-βAla-β-glucuronide-MMAE can be used for the synthesis of ADC.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.78%
- CAS 番号: 3130393-27-7
- 分子式: C63H92N8O20
- 分子量:1281.45
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Antibody-drug conjugates (ADCs) consist of drug-linker conjugates composed of active cytotoxic drugs and appropriate linkers. After conjugation with monoclonal antibodies, these conjugates can be used to prepare ADCs, which are highly selective and cytotoxic targeted drugs against cancer cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3130393-27-7
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性状 Solid
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分子量 1281.45
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分子式 C63H92N8O20
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC(NC(CCNC(CCN4C(C=CC4=O)=O)=O)=O)=C(C=C3)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)=O)=O)=O)=O)OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (78.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7804 mL | 3.9018 mL | 7.8037 mL | 19.5092 mL |
| 5 mM | 0.1561 mL | 0.7804 mL | 1.5607 mL | 3.9018 mL | |
| 10 mM | 0.0780 mL | 0.3902 mL | 0.7804 mL | 1.9509 mL | |
| 15 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3006 mL | |
| 20 mM | 0.0390 mL | 0.1951 mL | 0.3902 mL | 0.9755 mL | |
| 25 mM | 0.0312 mL | 0.1561 mL | 0.3121 mL | 0.7804 mL | |
| 30 mM | 0.0260 mL | 0.1301 mL | 0.2601 mL | 0.6503 mL | |
| 40 mM | 0.0195 mL | 0.0975 mL | 0.1951 mL | 0.4877 mL | |
| 50 mM | 0.0156 mL | 0.0780 mL | 0.1561 mL | 0.3902 mL | |
| 60 mM | 0.0130 mL | 0.0650 mL | 0.1301 mL | 0.3252 mL |
Mal-βAla-β-glucuronide-MMAE 関連分類
HY-185908 関連分類
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