Mal-βAla-β-glucuronide-MMAE
Based on 1 Customer Validation
Mal-βAla-β-glucuronide-MMAE is a drug-linker conjugate. Mal-βAla-β-glucuronide-MMAE can be used for the synthesis of ADC.
For research use only. We do not sell to patients.
- Purity : 99.78%
- CAS No.: 3130393-27-7
- Formula: C63H92N8O20
- Molecular Weight:1281.45
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
In Vitro
Antibody-drug conjugates (ADCs) consist of drug-linker conjugates composed of active cytotoxic drugs and appropriate linkers. After conjugation with monoclonal antibodies, these conjugates can be used to prepare ADCs, which are highly selective and cytotoxic targeted drugs against cancer cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3130393-27-7
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Appearance Solid
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Molecular Weight 1281.45
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Formula C63H92N8O20
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC(NC(CCNC(CCN4C(C=CC4=O)=O)=O)=O)=C(C=C3)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (78.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7804 mL | 3.9018 mL | 7.8037 mL | 19.5092 mL |
| 5 mM | 0.1561 mL | 0.7804 mL | 1.5607 mL | 3.9018 mL | |
| 10 mM | 0.0780 mL | 0.3902 mL | 0.7804 mL | 1.9509 mL | |
| 15 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3006 mL | |
| 20 mM | 0.0390 mL | 0.1951 mL | 0.3902 mL | 0.9755 mL | |
| 25 mM | 0.0312 mL | 0.1561 mL | 0.3121 mL | 0.7804 mL | |
| 30 mM | 0.0260 mL | 0.1301 mL | 0.2601 mL | 0.6503 mL | |
| 40 mM | 0.0195 mL | 0.0975 mL | 0.1951 mL | 0.4877 mL | |
| 50 mM | 0.0156 mL | 0.0780 mL | 0.1561 mL | 0.3902 mL | |
| 60 mM | 0.0130 mL | 0.0650 mL | 0.1301 mL | 0.3252 mL |
Mal-βAla-β-glucuronide-MMAE Related Classifications
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