MDM2-IN-27
MDM2-IN-27 (Compound 20k) is an MDM2 inhibitor. MDM2-IN-27 can effectively block the inhibitory effect of MDM2 on p53, thereby activating the p53 pathway. MDM2-IN-27 has a certain topoisomerase I inhibitory activity and has a very weak inhibitory effect on topoisomerase IIα. MDM2-IN-27 exhibits significant anti-proliferative activity against breast cancer, colon cancer, and cutaneous squamous cell carcinoma.
For research use only. We do not sell to patients.
- Formula: C29H38NO9PS
- Molecular Weight:607.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 607.65
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Formula C29H38NO9PS
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SMILES
S=P(OCC)(N(C/C(C/1=O)=C\C2=CC(OC)=C(OC)C(OC)=C2)CC1=C/C3=CC(OC)=C(OC)C(OC)=C3)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)