Methyl-L-NIO hydrochloride
Methyl-L-NIO (compound 2d) hydrochloride is a potential selective inhibitor (IC50: 70 μM) of dimethylarginine dimethylaminohydrolase hDDAH. Methyl-L-NIO also has inhibitory activity against NO synthase. The inhibition rates of Methyl-L-NIO on different isoforms of NO synthase at a concentration of 100 μM are 77% (nNOS), 20% (eNOS), and 72% (iNOS) respectively; the inhibition rates at a concentration of 1 mM are 100% (nNOS), 85% (eNOS), 100% (iNOS).
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- CAS No.: 150403-96-6
- Formula: C8H18ClN3O2
- Molecular Weight:223.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 70 μM (hDDAH, Dimethylarginine dimethylaminohydrolase)[1]
Chemical Information
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CAS No. 150403-96-6
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Molecular Weight 223.70
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Formula C8H18ClN3O2
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SMILES
N[C@@H](CCCNC(CC)=N)C(O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyl-L-NIO hydrochloride Related Classifications
HY-139135 Related Classifications
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