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  3. MODAG-001


Cat. No.: HY-150209 Purity: 98.19%
COA Handling Instructions

MODAG-001 can bind to synuclein fibrils in a rat brain. MODAG-001 is a candidate α-syn imaging probe.

For research use only. We do not sell to patients.

MODAG-001 Chemical Structure

MODAG-001 Chemical Structure

CAS No. : 2648041-72-7

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MODAG-001 can bind to synuclein fibrils in a rat brain. MODAG-001 is a candidate α-syn imaging probe[1][2][3].

In Vitro

MODAG-001 shows strong binding affinity to recombinant human α-syn aggregates, but fail to bind real α-syn aggregates in human brain sections[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (72.84 mM; Need ultrasonic)

Methanol : 4.9 mg/mL (14.28 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9136 mL 14.5679 mL 29.1358 mL
5 mM 0.5827 mL 2.9136 mL 5.8272 mL
10 mM 0.2914 mL 1.4568 mL 2.9136 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 4.17 mg/mL (12.15 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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