N1-Acetylspermine trihydrochloride

Name: N1-Acetylspermine trihydrochloride
Brand: MedChemExpress
SKU: HY-113200A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113200A Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia.

For research use only. We do not sell to patients.

N1-Acetylspermine trihydrochloride Chemical Structure

CAS No. : 77928-70-2

Size	Price	Stock	Quantity
5 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia^[1]^[2].

In Vitro

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

353.76

Formula

C₁₂H₃₁Cl₃N₄O

CAS No.

77928-70-2

Appearance

Solid

Color

White to off-white

SMILES

CC(NCCCNCCCCNCCCN)=O.Cl.Cl.Cl

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (141.34 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8268 mL	14.1339 mL	28.2678 mL
5 mM	0.5654 mL	2.8268 mL	5.6536 mL
10 mM	0.2827 mL	1.4134 mL	2.8268 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (267 KB) SDS (0 KB)

COA (242 KB)

Handling Instructions (2659 KB)

References

[1]. Lee SH, et al. Polyamine profiles in the urine of patients with leukemia. Cancer Lett. 1998 Jan 9;122(1-2):1-8. [Content Brief]

[2]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.8268 mL	14.1339 mL	28.2678 mL	70.6694 mL
	5 mM	0.5654 mL	2.8268 mL	5.6536 mL	14.1339 mL
	10 mM	0.2827 mL	1.4134 mL	2.8268 mL	7.0669 mL
	15 mM	0.1885 mL	0.9423 mL	1.8845 mL	4.7113 mL
	20 mM	0.1413 mL	0.7067 mL	1.4134 mL	3.5335 mL
	25 mM	0.1131 mL	0.5654 mL	1.1307 mL	2.8268 mL
	30 mM	0.0942 mL	0.4711 mL	0.9423 mL	2.3556 mL
	40 mM	0.0707 mL	0.3533 mL	0.7067 mL	1.7667 mL
	50 mM	0.0565 mL	0.2827 mL	0.5654 mL	1.4134 mL
	60 mM	0.0471 mL	0.2356 mL	0.4711 mL	1.1778 mL
	80 mM	0.0353 mL	0.1767 mL	0.3533 mL	0.8834 mL
	100 mM	0.0283 mL	0.1413 mL	0.2827 mL	0.7067 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.