N1-Acetylspermine
N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia.
For research use only. We do not sell to patients.
- CAS No.: 25593-72-0
- Formula: C12H28N4O
- Molecular Weight:244.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
>100 μM
Compound: Ac-SPM
|
Compound was tested for the growth inhibition of murine L1210 cell at a duration of 48 h
Compound was tested for the growth inhibition of murine L1210 cell at a duration of 48 h
|
[PMID: 14640556] |
| L1210 | IC50 |
>100 μM
Compound: Ac-SPM
|
Compound was tested for the growth inhibition of murine L1210 cell at a duration of 96 h
Compound was tested for the growth inhibition of murine L1210 cell at a duration of 96 h
|
[PMID: 14640556] |
| MDA-MB-231 | EC50 |
>1000 μM
Compound: 2
|
Effective concentration of compound with DFMO tested in vitro for ability to inhibit polyamine transport and growth of MDA-MB-231 breast carcinoma cell line
Effective concentration of compound with DFMO tested in vitro for ability to inhibit polyamine transport and growth of MDA-MB-231 breast carcinoma cell line
|
[PMID: 11738568] |
Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25593-72-0
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Molecular Weight 244.38
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Formula C12H28N4O
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SMILES
CC(NCCCNCCCCNCCCN)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)