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製品番号: HY-113200

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N1-Acetylspermine

N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 25593-72-0
分子式: C₁₂H₂₈N₄O
分子量:244.38

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

N1-Acetylspermine 構造式

CAS 番号: 25593-72-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体外実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia^[1]^[2].

IC₅₀ & Target

Human Endogenous Metabolite

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	>100 μM Compound: Ac-SPM	Compound was tested for the growth inhibition of murine L1210 cell at a duration of 48 h Compound was tested for the growth inhibition of murine L1210 cell at a duration of 48 h	[PMID: 14640556]
L1210	IC₅₀	>100 μM Compound: Ac-SPM	Compound was tested for the growth inhibition of murine L1210 cell at a duration of 96 h Compound was tested for the growth inhibition of murine L1210 cell at a duration of 96 h	[PMID: 14640556]
MDA-MB-231	EC₅₀	>1000 μM Compound: 2	Effective concentration of compound with DFMO tested in vitro for ability to inhibit polyamine transport and growth of MDA-MB-231 breast carcinoma cell line Effective concentration of compound with DFMO tested in vitro for ability to inhibit polyamine transport and growth of MDA-MB-231 breast carcinoma cell line	[PMID: 11738568]

体外実験

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 25593-72-0
分子量 244.38
分子式 C₁₂H₂₈N₄O
SMILES

CC(NCCCNCCCCNCCCN)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (262 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [Content Brief]

[2]. Lee SH, et al. Polyamine profiles in the urine of patients with leukemia. Cancer Lett. 1998 Jan 9;122(1-2):1-8. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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N1-Acetylspermine

Endogenous Metabolite アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

N1-Acetylspermine 関連分類

HY-113200 関連分類