NLRP3-IN-4
NLRP3-IN-4 is potent and orally active NLRP3 inflammasome inhibitor with inflammatory activity for colitis.
For research use only. We do not sell to patients.
- CAS No.: 2758595-77-4
- Formula: C22H22N2O5
- Molecular Weight:394.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
NLRP3 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L02 | IC50 |
>100 μM
Compound: 47
|
Cytotoxicity against human L-02 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human L-02 cells incubated for 24 hrs by MTT assay
|
[PMID: 34506712] |
Chemical Information
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CAS No. 2758595-77-4
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Molecular Weight 394.42
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Formula C22H22N2O5
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SMILES
COC1=CC(OC)=CC(/C=C/C2=CC=C(C=C2)NC(C3CC3)=O)=C1/C=C/[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)