NVP-TNKS656 (GMP) is NVP-TNKS656 (HY-13990) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2.
For research use only. We do not sell to patients.
- CAS No.: 1419949-20-4
- Formula: C27H34N4O5
- Molecular Weight:494.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.0035 μM
Compound: 43, NVP-TNKS656
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Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolin
Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolin
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[PMID: 23844574] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1419949-20-4
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Molecular Weight 494.58
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Formula C27H34N4O5
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SMILES
O=C(N(CC1CC1)CC2=NC3=C(COCC3)C(N2)=O)CN4CCC(C(C5=CC=C(OC)C=C5)=O)CC4
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Synonyms
TNKS656 (GMP)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NVP-TNKS656 (GMP) Related Classifications
HY-13990G Related Classifications
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