1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
    Apoptosis
  2. mAChR
    Angiotensin-converting Enzyme (ACE)
    Apoptosis
  3. Peimisine hydrochloride

Peimisine hydrochloride  (Synonyms: Ebeiensine hydrochloride)

Cat. No.: HY-N0214A
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Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research.

For research use only. We do not sell to patients.

Peimisine hydrochloride Chemical Structure

Peimisine hydrochloride Chemical Structure

CAS No. : 900498-44-4

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Description

Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research[1][2][3].

In Vitro

Peimisine (17.43-92.07 μg/mL; 72 h) shows significant cytotoxic effects[3].
Peimisine (15 μg/mL; 24, 48 and 72 h) induces G0/G1 phase arrest and rising apoptosis rate[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[2]

Cell Line: A2780 cells
Concentration: 15 μg/mL
Incubation Time: 24, 48 and 72 hours
Result: Induced G0/G1 phase arrest of A2780 cells in a time-dependent manner.

Cell Cytotoxicity Assay[2]

Cell Line: LLC, A2780, HepG2 and A549 cells
Concentration: 17.43-92.07 μg/mL
Incubation Time: 72 hours
Result: Inhibited LLC, A2780, HepG2 and A549 cells with the IC50 values of 20.75 μg/mL, 17.43 μg/mL, 92.07 μg/mL, 36.11 μg/mL, respectively.
Molecular Weight

464.08

Formula

C27H42ClNO3

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Peimisine hydrochloride
Cat. No.:
HY-N0214A
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