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Cat. No.: HY-N10285

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Phaeosphaone D

Phaeosphaone D is a thiodiketopiperazine alkaloid compound isolated from Phaeosphaeria fuckelii, an endophytic fungus. Phaeosphaone D displays mushroom tyrosinase inhibitory activity with an IC₅₀ value of 33.2 μM.

For research use only. We do not sell to patients.

CAS No.: 2640137-78-4
Formula: C₂₀H₂₇N₃O₃S₂
Molecular Weight:421.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Phaeosphaone D Chemical Structure

CAS No.: 2640137-78-4

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Biological Activity

Description

Phaeosphaone D is a thiodiketopiperazine alkaloid compound isolated from Phaeosphaeria fuckelii, an endophytic fungus. Phaeosphaone D displays mushroom tyrosinase inhibitory activity with an IC₅₀ value of 33.2 μM^[1].

Chemical Information

CAS No. 2640137-78-4
Molecular Weight 421.58
Formula C₂₀H₂₇N₃O₃S₂
SMILES

CS[C@H](C1=CNC2=CC=CC=C12)[C@]3(C(N([C@@](SC)(C(N3)=O)C(C)C)C)=O)OC
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
- Microorganisms
Phaeosphaeria fuckelii
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhai YJ, et al. Phaeosphaones: Tyrosinase Inhibitory Thiodiketopiperazines from an Endophytic Phaeosphaeria fuckelii. J Nat Prod. 2020;83(5):1592-1597. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References