2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3K-IN-36

PI3K-IN-36 (compound A68) is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL).

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PI3K-IN-36

PI3K-IN-36 Chemische Struktur

CAS. Nr. : 1401436-93-8

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
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10 mg Auf Lager
25 mg Auf Lager
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PI3K-IN-36 Related Antibodies

Top Publications Citing Use of Products

Alle PI3K Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Beschreibung

PI3K-IN-36 (compound A68) is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL)[1].

Molekulargewicht

562.66

Formel

C30H36F2N8O
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

FC(C1=NC2=C(N1C3=NC(NC(C)(CC4=C(C5CCNCC5)C=CC=C4)C)=NC(N6CCOCC6)=N3)C=CC=C2)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 12.5 mg/mL (22.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7773 mL 8.8864 mL 17.7727 mL
5 mM 0.3555 mL 1.7773 mL 3.5545 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7773 mL 8.8864 mL 17.7727 mL 44.4318 mL
5 mM 0.3555 mL 1.7773 mL 3.5545 mL 8.8864 mL
10 mM 0.1777 mL 0.8886 mL 1.7773 mL 4.4432 mL
15 mM 0.1185 mL 0.5924 mL 1.1848 mL 2.9621 mL
20 mM 0.0889 mL 0.4443 mL 0.8886 mL 2.2216 mL
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PI3K-IN-36 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K-IN-361401436-93-8PI3KPhosphoinositide 3-kinasefollicular lymphomaanticancerInhibitorinhibitorinhibit

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