PI3Kα-IN-15
PI3Kα-IN-15 is a potent PI3Kα inhibitor with an IC50 of 0.15?μM. PI3Kα-IN-15 also has acceptable anti-proliferative activity (inhibits SKOV-3, T47D, NCI-H1975, NCI-H460, and MCF-7 growth with IC50 values of 26.6?μM, 7.9?μM,? 32.1?μM,? 17.7??μM, and 9.4??μM, respectively. PI3Kα-IN-15 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2893920-80-2
- Formula: C25H24FN5O4S
- Molecular Weight:509.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2893920-80-2
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Molecular Weight 509.55
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Formula C25H24FN5O4S
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SMILES
O=S(C1=CC=C(F)C=C1)(NC2=CC(C3=CC(C)=CN4C3=NC(C(N5CCCC5)=O)=C4)=CN=C2OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)