PI3Kδ/γ-IN-1
Based on 1 Customer Validation
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 1980884-01-2
- Formula: C25H28N6O4S
- Molecular Weight:508.59
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
1.4 μM
Compound: 12; FMF-02-063-1
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Antiproliferative activity against human Jurkat cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human Jurkat cells after 3 days by CellTiter-Glo assay
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[PMID: 27774127] |
| Jurkat | IC50 |
1400 nM
Compound: 119
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Cytotoxicity against human Jurkat cells
Cytotoxicity against human Jurkat cells
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[PMID: 30582813] |
| LOUCY | IC50 |
0.35 μM
Compound: 12; FMF-02-063-1
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Antiproliferative activity against human Loucy cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human Loucy cells after 3 days by CellTiter-Glo assay
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[PMID: 27774127] |
| MOLM-14 | IC50 |
1 μM
Compound: 12; FMF-02-063-1
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Antiproliferative activity against human MOLM14 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MOLM14 cells after 3 days by CellTiter-Glo assay
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[PMID: 27774127] |
| MOLT-4 | IC50 |
1.3 μM
Compound: 12; FMF-02-063-1
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Antiproliferative activity against human MOLT4 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MOLT4 cells after 3 days by CellTiter-Glo assay
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[PMID: 27774127] |
| MV4-11 | IC50 |
0.62 μM
Compound: 12; FMF-02-063-1
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Antiproliferative activity against human MV4-11 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MV4-11 cells after 3 days by CellTiter-Glo assay
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[PMID: 27774127] |
Chemical Information
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CAS No. 1980884-01-2
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Appearance Solid
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Molecular Weight 508.59
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Formula C25H28N6O4S
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Color Off-white to gray
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SMILES
O=C1N(C)C2=CN=C(NC3=CC=CC(S(=O)(N4CCC(O)CC4)=O)=C3)N=C2N(C)C5=CC=C(C)C=C15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 2.22 mg/mL (4.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9662 mL | 9.8311 mL | 19.6622 mL | 49.1555 mL |
PI3Kδ/γ-IN-1 Related Classifications
HY-144993 Related Classifications
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