1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Pinacidil

Pinacidil (Synonyms: P-1134)

Cat. No.: HY-14290 Purity: 98.66%
Handling Instructions

Pinacidil is a potent activator of potassium channel. Pinacidil is an antihypertensive agent which hyperpolarises vascular smooth muscle by opening K+-channels. Pinacidil significantly improves the reperfusion function and cardiac compliance. Pinacidil has direct cardioprotective efficacy.

For research use only. We do not sell to patients.

Pinacidil Chemical Structure

Pinacidil Chemical Structure

CAS No. : 60560-33-0

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5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
25 mg USD 160 In-stock
Estimated Time of Arrival: December 31
50 mg USD 260 In-stock
Estimated Time of Arrival: December 31
100 mg USD 410 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Pinacidil:

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Description

Pinacidil is a potent activator of potassium channel. Pinacidil is an antihypertensive agent which hyperpolarises vascular smooth muscle by opening K+-channels. Pinacidil significantly improves the reperfusion function and cardiac compliance. Pinacidil has direct cardioprotective efficacy[1].

IC50 & Target

potassium channel[1]

Molecular Weight

245.32

Formula

C13H19N5

CAS No.
SMILES

CC(C(C)(C)C)N/C(NC1=CC=NC=C1)=N\C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (407.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0763 mL 20.3815 mL 40.7631 mL
5 mM 0.8153 mL 4.0763 mL 8.1526 mL
10 mM 0.4076 mL 2.0382 mL 4.0763 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Pinacidil
Cat. No.:
HY-14290
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