PRKD2/PKD2
Sharing the tandem C1 domain-kinase architecture of the PKD family, PKD2 (gene PRKD2) is a Ser/Thr kinase activated by diacylglycerol and by PKC-dependent phosphorylation of its activation loop. It localizes to the Golgi apparatus and participates in protein transport, secretory pathways and integrin-mediated signaling. PKD2 is expressed in many tissues, including heart and skeletal muscle, but its function remains less explored than that of PKD1 or PKD3. Emerging evidence links PKD2 to pancreatic cancer cell proliferation and to regulation of epithelial barrier function. Because it can partially compensate for other PKDs, isoform-selective tools are needed to define its unique biology.
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PRKD2/PKD2 Protéines Recombinantes (2)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
