PTP1B-IN-27
PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP‐1B)(IC50=8.2 µM). PTP1B-IN-27 also inhibits α-Glucosidase (IC50=120 µM) and shows competitive inhibition (Ki=118 µM).
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- Formule: C26H24FN7O2S
- Masse moléculaire:517.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
PTP1B-IN-27 (50 µM; 48 h) shows non-cytotoxicity against human dermal fibroblasts (HDF)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 517.58
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Formule C26H24FN7O2S
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SMILES
O=C(NCC1=CC=C(F)C=C1)CN2N=NC(COC3=CC=C(/C=N/NC(NC4=CC=CC=C4)=S)C=C3)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)