PTP1B-IN-27
PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP‐1B)(IC50=8.2 µM). PTP1B-IN-27 also inhibits α-Glucosidase (IC50=120 µM) and shows competitive inhibition (Ki=118 µM).
For research use only. We do not sell to patients.
- Formula: C26H24FN7O2S
- Molecular Weight:517.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
PTP1B-IN-27 (50 µM; 48 h) shows non-cytotoxicity against human dermal fibroblasts (HDF)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 517.58
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Formula C26H24FN7O2S
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SMILES
O=C(NCC1=CC=C(F)C=C1)CN2N=NC(COC3=CC=C(/C=N/NC(NC4=CC=CC=C4)=S)C=C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)