Chemical constituents and biological activities of Zanthoxylum usambarense

  • Phytother Res. 2002 Feb;16(1):66-70. doi: 10.1002/ptr.849.
Weidong He  1 ,  Luc Van Puyvelde ,  Norbert De Kimpe ,  Luc Verbruggen ,  Kristel Anthonissen ,  Mark Van der Flaas ,  Jan Bosselaers ,  Simon G Mathenge ,  Francis P Mudida
Affiliations
  • 1. Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, University of Gent, Coupure Links 653, B-9000 Gent, Belgium.
PMID: 11807969 DOI: 10.1002/ptr.849
Abstract

Bioassay-guided fractionation of the dichloromethane extracts of the roots and the bark of Zanthoxylum usambarense led to the isolation of two physiologically active compounds, i.e. canthin-6-one 1 (fungicide) and pellitorine 4 (Insecticide). Together with oxychelerythrine 2, norchelerythrine 3, (+)-sesamin 5 and (+)-piperitol-3,3-dimethylallyl ether 6, they were isolated for the first time from this plant.

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