Inhibitory phenolic amides on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells from Beta vulgaris var. cicla seeds

  • Phytother Res. 2003 Sep;17(8):983-5. doi: 10.1002/ptr.1232.
Youngleem Kim  1 ,  Mi Seon Han ,  Ji Suk Lee ,  Jinwoong Kim ,  Young Choong Kim
Affiliations
  • 1. College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Korea.
PMID: 13680842 DOI: 10.1002/ptr.1232
Abstract

Four phenolic compounds were isolated from Beta vulgaris L. var. cicla L. (Chenopodiaceae). These isolated compounds were identified as N-cis-feruloyl 3-O-methyldopamine (1), N-cis-feruloyl tyramine (2), N-trans-feruloyl 3-O-methyldopamine (3), N-trans-feruloyl tyramine (4), respectively, by spectroscopic analysis. The phenolic amides 1-4 exhibited modest inhibitory activity on LPS-activated nitric oxide production dose-dependently in RAW 264.7 cells.

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