Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus

  • Phytochemistry. 2004 Apr;65(7):969-74. doi: 10.1016/j.phytochem.2003.11.013.
Hong-Bing Wang  1 Hui Yao Guan-Hu Bao Hua-Ping Zhang Guo-Wei Qin
Affiliations
  • 1. Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
Abstract

Three flavone glucosides, pleiosides A-C, were isolated from the leaves of Pleioblastus amarus, along with two known flavones: tricin and tricetin 3,5-dimethoxy-7-O-beta-d-glucopyranoside. Their structures were elucidated by extensive spectral studies. Pleiosides A-C were found to inhibit the proliferation of murine T and significantly stimulate the proliferation of murine B lymphocytes in vitro.

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