Norisoprenoids and hepatoprotective flavone glycosides from the aerial parts of Beta vulgaris var. cicla

  • Arch Pharm Res. 2004 Jun;27(6):600-3. doi: 10.1007/BF02980156.
Inkyum Kim  1 ,  Young-Won Chin ,  Song Won Lim ,  Young Choong Kim ,  Jinwoong Kim
Affiliations
  • 1. College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea.
PMID: 15283459 DOI: 10.1007/BF02980156
Abstract

(+)-Dehydrovomifoliol (1), 3-hydroxy-5alpha,6alpha-epoxy-beta-ionone (2), vitexin 7-O-beta-D-glucopyranoside (3), and vitexin 2''-O-beta-D-glucopyranoside (4) were isolated as new constituents from the aerial parts of Beta vulgaris var. cicla. Compounds 3 and 4 demonstrated hepatoprotective activity with values of 65.8 and 56.1%, respectively, in primary cultured rat hepatocytes with CCl4-induced cell toxicity, compared to controls. This was comparable to that of silibinin (69.8 %) which was used as a positive control.

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