Chemical constituents of the roots of Piper sarmentosum

  • Chem Pharm Bull (Tokyo). 2006 Feb;54(2):149-51. doi: 10.1248/cpb.54.149.
Pittaya Tuntiwachwuttikul  1 ,  Photchana Phansa ,  Yupa Pootaeng-On ,  Walter Charles Taylor
Affiliations
  • 1. Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom, Thailand. [email protected]
PMID: 16462055 DOI: 10.1248/cpb.54.149
Abstract

Sixteen compounds were isolated from the fresh roots of Piper sarmentosum. Seven of these have been previously isolated from the fruits and leaves of this plant: the aromatic alkene (1), 1-allyl-2-methoxy-4,5-methylenedioxybenzene (4), beta-sitosterol, pyrrole amide (6), sarmentine (10), sarmentosine (13) and pellitorine (14). (+)-Sesamin (2), horsfieldin (3), two pyrrolidine amides 11 and 12, guineensine (15) and brachystamide B (16) are new for P. sarmentosum. Sarmentamide A, B, and C (7-9) are new natural products. Compounds 1--4 and 6--16 were tested for antiplasmodial, antimycobacterial and Antifungal activities.

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