Cysteine proteinase inhibitors in murine cysticercosis

  • Antimicrob Agents Chemother. 2006 Aug;50(8):2886-8. doi: 10.1128/AAC.01060-05.
Salman Baig  1 ,  Raymond T Damian ,  Jorge Morales-Montor ,  Rupal Thazhath ,  Amr Ghaleb ,  Meredith Welch ,  Jamil Talhouk ,  A Clinton White Jr
Affiliations
  • 1. Department of Cellular Biology, University of Georgia, Athens, Georgia 30603, USA.
PMID: 16870795 DOI: 10.1128/AAC.01060-05
Abstract

We explored the prophylactic efficacies of two novel Protease Inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in Parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

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