Z-Leu-Leu-Leu-fluoromethyl ketone
Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a cysteine protease inhibitor. Z-Leu-Leu-Leu-fluoromethyl ketone inhibits SARS infection. Z-Leu-Leu-Leu-fluoromethyl ketone also protects mice against a T. crassiceps challenge.
For research use only. We do not sell to patients.
- CAS No.: 371167-61-2
- Formula: C27H42FN3O5
- Molecular Weight:507.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Cathepsin Isoforms
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Biological Activity
Description
IC50 & Target
cysteine protease[1].
Chemical Information
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CAS No. 371167-61-2
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Molecular Weight 507.64
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Formula C27H42FN3O5
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Synonyms
Z-LLL-FMK
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Sequence
Z-Leu-Leu-Leu-FMK
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Sequence Shortening
Z-LLL-FMK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Simmons G, et al. Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11876-81. [Content Brief]
[2]. Baig S, et al. Cysteine proteinase inhibitors in murine cysticercosis. Antimicrob Agents Chemother. 2006 Aug;50(8):2886-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Z-Leu-Leu-Leu-fluoromethyl ketone Related Classifications
HY-P5975 Related Classifications
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