Evaluation of the IMMY ALPHA Histoplasma antigen enzyme immunoassay for diagnosis of histoplasmosis marked by antigenuria

  • Clin Vaccine Immunol. 2007 Jun;14(6):802-3. doi: 10.1128/CVI.00035-07.
Ann LeMonte  1 ,  Lindsey Egan ,  Patricia Connolly ,  Michelle Durkin ,  L Joseph Wheat
Affiliations
  • 1. MiraVista Diagnostics and MiraBella Technologies, 4444 Decatur Blvd., Indianapolis, IN 46241, USA. [email protected]
PMID: 17409220 DOI: 10.1128/CVI.00035-07
Abstract

The sensitivity of detection of antigenuria in patients positive by the MiraVista Diagnostics Histoplasma enzyme Immunoassay (MVD EIA) was 44% with the IMMY ALPHA Histoplasma antigen EIA. The specificity was 84% with the IMMY EIA versus 98% with the MVD EIA. The correlation between assays for positive cases was weak (r(2) = 0.430).