Bisnorditerpene, norditerpene, and lipo-alkaloids from Aconitum toxicum

  • J Nat Prod. 2008 Oct;71(10):1779-82. doi: 10.1021/np800322q.
Dezso Csupor  1 ,  Peter Forgo ,  Eva Maria Wenzig ,  Rudolf Bauer ,  Judit Hohmann
Affiliations
  • 1. Department of Pharmacognosy, University of Szeged, Szeged, Hungary.
PMID: 18841905 DOI: 10.1021/np800322q
Abstract

From the roots of Aconitum toxicum, acotoxicine (1), a new bisnorditerpene alkaloid, was isolated together with the structurally related delavaconitine, delavaconine, dolaconine, aconosine, and the norditerpene alkaloid neolinine. The structure of compound 1 was elucidated by spectroscopic data interpretation. Further, eight lipo-alkaloids (2-9) were detected in the plant material by LC-APCI-MSn analysis. This is the first report of a C18 bisnorditerpene alkaloid and lipo-alkaloids from A. toxicum.

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