A new monoterpenoid glycoside from Myrica esculenta and the inhibition of angiotensin I-converting enzyme
- Chem Pharm Bull (Tokyo). 2010 Oct;58(10):1408-10. doi: 10.1248/cpb.58.1408.
Affiliations
- 1. College of Pharmacy, Chungnam National University, Daejeon 305–764, Korea.
PMID: 20930414
DOI: 10.1248/cpb.58.1408
Abstract
One new monoterpenoid glycoside, myresculoside (1), and eleven known compounds, were isolated from methanol extract of Myrica esculenta leaves by repeated column chromatography. The effects of these compounds on angiotensin I-converting enzyme (ACE) inhibition were investigated. Compounds 3 and 4 showed the most potent ACE inhibition with rates of 29.97% and 25.63% at concentration of 100 µM, respectively. Compounds 5, 6, and 11 showed weak activity with inhibitory rates of 0.07-1.41% at concentration of 100 µM.
Products
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Cat. No.Product NameDescriptionTargetResearch Area
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target: Angiotensin ReceptorResearch Areas: Others