P2Y12 receptor in platelet activation

  • Platelets. 2011;22(1):56-60. doi: 10.3109/09537104.2010.497231.
Soochong Kim  1 ,  Satya P Kunapuli
Affiliations
  • 1. Department of Physiology, Temple University School of Medicine, Philadelphia, PA, USA.
PMID: 21231822 DOI: 10.3109/09537104.2010.497231
Abstract

ADP plays an important role in hemostasis and thrombosis. The P2Y12 Receptor, activated by ADP, plays a central role in platelet activation and thrombus formation. Thus, the P2Y12 Receptor has been an effective target for antithrombotic drugs.