Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

  • Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f.
Paul G Arnison  1 ,  Mervyn J Bibb ,  Gabriele Bierbaum ,  Albert A Bowers ,  Tim S Bugni ,  Grzegorz Bulaj ,  Julio A Camarero ,  Dominic J Campopiano ,  Gregory L Challis ,  Jon Clardy ,  Paul D Cotter ,  David J Craik ,  Michael Dawson ,  Elke Dittmann ,  Stefano Donadio ,  Pieter C Dorrestein ,  Karl-Dieter Entian ,  Michael A Fischbach ,  John S Garavelli ,  Ulf Göransson ,  Christian W Gruber ,  Daniel H Haft ,  Thomas K Hemscheidt ,  Christian Hertweck ,  Colin Hill ,  Alexander R Horswill ,  Marcel Jaspars ,  Wendy L Kelly ,  Judith P Klinman ,  Oscar P Kuipers ,  A James Link ,  Wen Liu ,  Mohamed A Marahiel ,  Douglas A Mitchell ,  Gert N Moll ,  Bradley S Moore ,  Rolf Müller ,  Satish K Nair ,  Ingolf F Nes ,  Gillian E Norris ,  Baldomero M Olivera ,  Hiroyasu Onaka ,  Mark L Patchett ,  Joern Piel ,  Martin J T Reaney ,  Sylvie Rebuffat ,  R Paul Ross ,  Hans-Georg Sahl ,  Eric W Schmidt ,  Michael E Selsted ,  Konstantin Severinov ,  Ben Shen ,  Kaarina Sivonen ,  Leif Smith ,  Torsten Stein ,  Roderich D Süssmuth ,  John R Tagg ,  Gong-Li Tang ,  Andrew W Truman ,  John C Vederas ,  Christopher T Walsh ,  Jonathan D Walton ,  Silke C Wenzel ,  Joanne M Willey ,  Wilfred A van der Donk
Affiliations
  • 1. Prairie Plant Systems Inc, Botanical Alternatives Inc, Suite 176, 8B-3110 8th Street E, Saskatoon, SK, S7H 0W2, Canada.
Abstract

This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified Peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.

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