A case of capecitabine-induced sarcoidosis

  • Tuberc Respir Dis (Seoul). 2012 Mar;72(3):318-22. doi: 10.4046/trd.2012.72.3.318.
Shin Myung Kang  1 ,  Ji Yeon Baek ,  Bin Hwangbo ,  Hyae-Young Kim ,  Geon-Kook Lee ,  Hee Seok Lee
Affiliations
  • 1. Center for Lung Cancer, National Cancer Center, Goyang, Korea. ; Department of Pulmonary and Critical Care Medicine, Gachon University Gil Hospital, Incheon, Korea.
PMID: 23227072 DOI: 10.4046/trd.2012.72.3.318
Abstract

Sarcoidosis is an inflammatory disease involving multiple-organs with an unknown cause. The new onset of sarcoidosis associated with therapeutic agents has been observed in 3 clinical settings; tumor necrosis factor antagonists in autoimmune rheumatologic diseases, interferon Alpha with or without ribavirin in patients with chronic hepatitis C or Melanoma, and antineoplastic agent-associated sarcoidosis in patients with hematologic malignancies. Here, we report a female patient who developed sarcoidosis after capecitabine treatment as an Adjuvant chemotherapy for sigmoid colon Cancer. To our knowledge, this is the first report of a capecitabine-induced sarcoidosis.

Keywords
Capecitabine; Sarcoidosis; Sigmoid Neoplasms.