New clerodane diterpenes from Tinospora sagittata var. yunnanensis

  • Planta Med. 2014 Mar;80(5):419-25. doi: 10.1055/s-0034-1368252.
Zhi-Yong Jiang  1 ,  Wen-Juan Li  1 ,  Li-Xiang Jiao  1 ,  Jun-Ming Guo  1 ,  Kai Tian  1 ,  Chun-Tao Yang  1 ,  Xiang-Zhong Huang  1
Affiliations
  • 1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Yunnan, P. R. China.
PMID: 24634023 DOI: 10.1055/s-0034-1368252
Abstract

Four new clerodane diterpenes, namely sagittatayunnanosides A-D (1-4), were isolated from the roots of Tinospora sagittata var. yunnanensis, together with two known compounds, tinospinoside C (5) and tinospinoside E (6). The structures of the four new compounds were well elucidated by extensive analyses of the MS, IR, and 1D and 2D NMR data. The cytotoxic and antifouling activities of compounds 1-6 were evaluated.

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