Janus kinase inhibition for autoinflammation in patients with DNASE2 deficiency

  • J Allergy Clin Immunol. 2020 Feb;145(2):701-705.e8. doi: 10.1016/j.jaci.2019.11.020.
Ying Hong  1 ,  Melania Capitani  2 ,  Claire Murphy  3 ,  Sumeet Pandey  2 ,  Athena Cavounidis  2 ,  Haruo Takeshita  4 ,  Sira Nanthapisal  5 ,  Toshihiro Yasuda  6 ,  Brigitte Bader-Meunier  7 ,  Dara McCreary  8 ,  Ebun Omoyinmi  8 ,  Anupama Rao  9 ,  Claire Booth  3 ,  Kimberly Gilmour  9 ,  Neil Sebire  9 ,  Neil Shah  9 ,  Nigel Klein  3 ,  Alex N Bullock  10 ,  Despina Eleftheriou  11 ,  Holm H Uhlig  2 ,  Paul Brogan  3
Affiliations
  • 1. University College London Great Ormond Street Institute of Child Health, London, United Kingdom. Electronic address: [email protected].
  • 2. Translational Gastroenterology Unit, Department of Pediatrics, and Oxford Biomedical Research Centre (BRC), University of Oxford, Oxford, United Kingdom.
  • 3. University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • 4. Department of Legal Medicine, Shimane University, Shimane, Japan.
  • 5. University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Thammasat University, Bangkok, Thailand.
  • 6. Department of Medical Genetics and Biochemistry, University of Fukui, Fukui, Japan.
  • 7. Department of Pediatric Immunology and Rheumatology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • 8. University College London Great Ormond Street Institute of Child Health, London, United Kingdom.
  • 9. Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • 10. Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • 11. University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom; Arthritis Research UK Centre for Adolescent Rheumatology, UCL, London, United Kingdom.
PMID: 31775019 DOI: 10.1016/j.jaci.2019.11.020