Novel Azepinoindoles as 5‑HT2C Agonists for Treating Depression, Drug Addiction, Alcoholism, PTSD, and Neuropathic Pain

  • ACS Med Chem Lett. 2025 Jul 28;16(8):1507-1508. doi: 10.1021/acsmedchemlett.5c00426.
Ram W Sabnis  1
Affiliations
  • 1. Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Atlanta, Georgia 30309, United States.
PMID: 40832530 DOI: 10.1021/acsmedchemlett.5c00426
Abstract

Provided herein are novel azepinoindoles as 5-HT2C agonists, pharmaceutical compositions, use of such compounds in treating depression, drug addiction, alcoholism, post-traumatic stress disorder (PTSD), and neuropathic pain, and processes for preparing such compounds.

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