Rubiadin, a new antioxidant from Rubia cordifolia

  • Indian J Biochem Biophys. 1997 Jun;34(3):302-6.
Y B Tripathi  1 M Sharma M Manickam
Affiliations
  • 1. Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.
PMID: 9425750
Abstract

Rubiadin, a dihydroxy anthraquinone, isolated from alcoholic extract of Rubia cordifolia, possesses potent antioxidant property. It prevents lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. The per cent inhibition was more in the case of Fe2+ induced lipid peroxidation. The antioxidant property of the preparation has been found to be better than that of EDTA, Tris, mannitol, Vitamin E and p-benzoquinone.

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