ROCK2-IN-20
ROCK2-IN-20 is a selective ROCK2 inhibitor with an IC50 value of 12 nM. ROCK2-IN-20 can be used for research on multiple sclerosis, pulmonary arterial hypertension, and glaucoma.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1219722-56-1
- Formule: C19H20N4O2
- Masse moléculaire:336.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
ROCK2 12 nM (IC50) |
PKA 610 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| A7R5 | IC50 |
59 nM
Compound: 12o
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Inhibition of ROCK-mediated myosin light chain bisphosphorylation in rat A7R5 cells after 1 hr by fluorescence assay in presence of L-alpha-lysophosphatidic acid
Inhibition of ROCK-mediated myosin light chain bisphosphorylation in rat A7R5 cells after 1 hr by fluorescence assay in presence of L-alpha-lysophosphatidic acid
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[PMID: 23570561] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1219722-56-1
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Masse moléculaire 336.40
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Formule C19H20N4O2
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SMILES
O=C(NC=1C=CC(=CC1)C=2C=NNC2)N(CC=3C=CC=CC3)CCO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ROCK2-IN-20 Related Classifications
HY-134146 Related Classifications
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