2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. RWJ 29009

RWJ 29009 is a highly selective ATP-sensitive potassium channel agonist. RWJ 29009 activates potassium channel in vascular smooth muscle cells, promoting potassium efflux and membrane hyperpolarization to induce coronary and peripheral vasodilation. RWJ 29009 is promising for research of cardiovascular diseases such as acute myocardial ischemia and hypertension.

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RWJ 29009

RWJ 29009 Chemical Structure

CAS No. : 143164-10-7

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Description

RWJ 29009 is a highly selective ATP-sensitive potassium channel agonist. RWJ 29009 activates potassium channel in vascular smooth muscle cells, promoting potassium efflux and membrane hyperpolarization to induce coronary and peripheral vasodilation. RWJ 29009 is promising for research of cardiovascular diseases such as acute myocardial ischemia and hypertension[1].

Molecular Weight

326.37

Formula

C14H18N2O5S
CAS No.
SMILES

O=C1N(CCCC1)[C@@H]2C3=C(OC(C)([C@H]2O)C)C=C(S3)[N+]([O-])=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
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RWJ 29009 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RWJ 29009143164-10-7RWJ29009RWJ-29009Potassium ChannelKcsApotassium channelvascular smooth muscle cellscardiovascular diseasesInhibitorinhibitorinhibit

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