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Cat. No.: HY-N21961

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Sceleratine N-oxide

Sceleratine N-oxide is a pyrrolizidine alkaloid N-oxide isolated from Senecio latifolius DC. As a secondary metabolite of toxic plants, Sceleratine N-oxide serves as one of the target analytes for LC-MS/MS detection of PA/PANO contamination in milk.

For research use only. We do not sell to patients.

CAS No.: 103184-92-5
Formula: C₁₈H₂₇NO₈
Molecular Weight:385.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Sceleratine N-oxide Chemical Structure

CAS No.: 103184-92-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Sceleratine N-oxide (0.05-3.00 µg/L) is quantitatively detectable in raw cow's milk via this validated LC-MS/MS method, with an LOQ of 0.047 µg/L, consistent recovery rates, and good repeatability across tested concentration levels^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103184-92-5
Molecular Weight 385.41
Formula C₁₈H₂₇NO₈
SMILES

OC[C@@]([C@H](C)[C@@H](C)[C@@](C)(O)C1=O)(C(O[C@H](CC2)[C@]3([H])[N+]2([O-])CC=C3CO1)=O)O
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bredenkamp M W, et al. A new pyrrolizidine alkaloid N-oxide and the revised structure of sceleratine[J]. Tetrahedron Letters, 1985, 26(46): 5721-5724.

[2]. Klein LM, et al. A sensitive LC-MS/MS method for isomer separation and quantitative determination of 51 pyrrolizidine alkaloids and two tropane alkaloids in cow's milk. Analytical and bioanalytical chemistry. 2022 Nov;414(28):8107-8124.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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