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Art. -Nr.: HY-N21961

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Sceleratine N-oxide

Sceleratine N-oxide is a pyrrolizidine alkaloid N-oxide isolated from Senecio latifolius DC. As a secondary metabolite of toxic plants, Sceleratine N-oxide serves as one of the target analytes for LC-MS/MS detection of PA/PANO contamination in milk.

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CAS. Nr.: 103184-92-5
Formel: C₁₈H₂₇NO₈
Molecular Weight:385.41

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Sceleratine N-oxide Chemical Structure

CAS. Nr.: 103184-92-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

In Vitro

Sceleratine N-oxide (0.05-3.00 µg/L) is quantitatively detectable in raw cow's milk via this validated LC-MS/MS method, with an LOQ of 0.047 µg/L, consistent recovery rates, and good repeatability across tested concentration levels^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 103184-92-5
Molecular Weight 385.41
Formel C₁₈H₂₇NO₈
SMILES

OC[C@@]([C@H](C)[C@@H](C)[C@@](C)(O)C1=O)(C(O[C@H](CC2)[C@]3([H])[N+]2([O-])CC=C3CO1)=O)O
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Bredenkamp M W, et al. A new pyrrolizidine alkaloid N-oxide and the revised structure of sceleratine[J]. Tetrahedron Letters, 1985, 26(46): 5721-5724.

[2]. Klein LM, et al. A sensitive LC-MS/MS method for isomer separation and quantitative determination of 51 pyrrolizidine alkaloids and two tropane alkaloids in cow's milk. Analytical and bioanalytical chemistry. 2022 Nov;414(28):8107-8124.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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