CA6 - carbonic anhydrase 6 Gene

Also Known as CA-VI; GUSTIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 765

About CA6

Cytogenetic location: 1p36.23 Genomic coordinates (GRCh38): 1:8,945,868-8,975,092 (from NCBI)

This gene has 6 transcripts (splice variants), 228 orthologues and 14 paralogues. Restricted expression toward salivary gland (RPKM 1381.7).

Summary

The protein encoded by this gene is one of several isozymes of Carbonic Anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]

CA6 Products (4)

mRNA Protein Name
NM_001215.4 NP_001206.2 carbonic anhydrase 6 isoform 1 precursor
NM_001270500.2 NP_001257429.1 carbonic anhydrase 6 isoform 2 precursor
NM_001270501.2 NP_001257430.1 carbonic anhydrase 6 isoform 3 precursor
NM_001270502.2 NP_001257431.1 carbonic anhydrase 6 isoform 4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: Inferred from direct assay
24248522 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
24248522 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CA6 Protein Structure

Carb_anhydrase

Carb_anhydrase: Eukaryotic-type carbonic anhydrase (23 - 278)

  • 0
  • 100
  • 200
  • 308 a.a.
Protein Preferred Names Protein Names

carbonic anhydrase 6

  • carbonate dehydratase VI

CA6 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810853 CA VI Antibody WB, IHC-P, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Mammary Analogue Secretory Carcinoma
Dental Caries

  • Dental Caries Extending Into Pulp

  • Dental Caries Of Smooth Surface

  • Dental Caries Pit And Fissure

  • Smooth Surface Dental Caries

  • Dental Decay

  • Carious Teeth

  • Dental Cavity

  • Saprodontia

  • Teeth Decayed

  • Tooth Caries

  • Tooth Decay
Enamel Erosion
Tooth Erosion

  • Generalized Erosion

  • Localized Erosion

  • Generalized Erosions

  • Erosion, Localized
Multilocular Clear Cell Renal Cell Carcinoma

  • Cystadenocarcinoma Of Kidney

  • Renal Cystadenocarcinoma
Aseptic Meningitis

  • Acute Aseptic Meningitis

  • Meningitis Aseptic

  • Meningitis, Aseptic
Parotid Disease

  • Parotid Diseases
Xerophthalmia

  • Conjunctival Xerosis
Potocki-Shaffer Syndrome

  • Proximal 11p Deletion Syndrome

  • Chromosome 11p11.2 Deletion Syndrome

  • Pss

  • 11p11.2 Deletion

  • P11pds

  • Defect11 Syndrome

  • Deletion Of Chromosome 11p11.2

  • POSHS
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01773 CA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991649 Anti-CA6 Antibody (huDS6) 98.03% Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CA6 VGNC VGNC:26656
Mus musculus CA6 MGD MGI:1333786
Macaca mulatta CA6 VGNC VGNC:70493
Felis catus CA6 VGNC VGNC:60277
Canis familiaris CA6 VGNC VGNC:38614
Rattus norvegicus CA6 RGD RGD:70516
Others CA6 NCBI